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State-of-the-art medical facilities are located within five miles of Ponte Vedra Beach. Mayo Clinic/Jacksonville has continually expanded its health care and research programs since its move to this area. This renowned Clinic attracts patients from around the world. Mayo Clinic Hospital, which opened in April 2008, brings inpatient and outpatient services under one roof. The new hospital has 214 beds and 22 operating rooms. It offers care in more than 35 medical and surgical specialties. The hospital includes a full service Emergency Department, open to everyone in the community.

Baptist Medical Center Beaches is just minutes to the north in Jacksonville Beach, and is housed in a new modern facility. Located in the heart of Ponte Vedra is Vicar's Landing, a total life care facility for our aging neighbors.

Affiliated with the University of Florida College of Medicine, Shands Jacksonville is one of this region's most acclaimed teaching hospitals. The University of Florida Proton Therapy Institute treats cancer patients with highly accurate doses of radiation that can increase the chance for cure with fewer side effects. It is the only Proton Therapy Center in the Southeast and one of only five in the U.S. Proton therapy is effective for treating some cancers in children and in sensitive areas like the head and neck, brain, eye, lung, breast, gastrointestinal tract and prostate. With the latest conventional radiation equipment and proton beam, Shands Jacksonville and the University of Florida Proton Therapy Institute offer patients the most advanced forms of external beam radiation therapy in the world in one setting. With world-renowned researchers and clinicians on staff, the UF College of Medicine at Shands Jacksonville consistently develops breakthroughs in diagnoses, cures and prevention.
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On April 12, 2008, two historic events occurred in Jacksonville that will change the face of the local healthcare landscape - the opening of the new Mayo Clinic Hospital and the official transfer of St. Luke's Hospital operations to St. Vincent's Healthcare.

Baptist Health is a faith-based, mission-driven healthcare organization comprised of Baptist Medical Center Downtown, Baptist Medical Center Beaches, Baptist Medical Center Nassau and Wolfson Children's Hospital - Jacksonville's only children's hospital.

Wolfson Children's Hospital is a regional referral hospital whose mission is to provide optimal healthcare services for infants and children. Nemours Children's Clinic and Shands/Jacksonville also play an integral role in the pediatric residency program, allowing these young professionals the opportunity to be involved with a nationally renowned faculty. Wolfson Children's Hospital is proud of its affiliation with the University of Florida/Jacksonville.

Nemours Children's Clinic in Jacksonville has 17 pediatric divisions providing world-class care to children with complex health problems and needs. Alfred I. DuPont left his family fortune in a Trust dedicated primarily to children's health care. Today, that vision is fulfilled in Nemours, one of the nation's leading children's health systems.